Biochemistry

Oberg F, Ekvall M, Nyblom M, Backmark A, Neutze R, Hedfalk K. Insight into factors directing high production of eukaryotic membrane proteins; production of 13 human AQPs in Pichia pastoris. Molecular membrane biology. 2009;26(4):215-27. Epub 2009/04/23.

Nyblom M, Frick A, Wang Y, Ekvall M, Hallgren K, Hedfalk K, et al. Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating. Journal of molecular biology. 2009;387(3):653-68. Epub 2009/03/24.

Fischer G, Kosinska-Eriksson U, Aponte-Santamaria C, Palmgren M, Geijer C, Hedfalk K, et al. Crystal structure of a yeast aquaporin at 1.15 angstrom reveals a novel gating mechanism. PLoS biology. 2009;7(6):e1000130. Epub 2009/06/17.

Hedfalk K, Pettersson N, Oberg F, Hohmann S, Gordon E. Production, characterization and crystallization of the Plasmodium falciparum aquaporin. Protein expression and purification. 2008;59(1):69-78. Epub 2008/02/26.

Nyblom M, Oberg F, Lindkvist-Petersson K, Hallgren K, Findlay H, Wikstrom J, et al. Exceptional overproduction of a functional human membrane protein. Protein expression and purification. 2007;56(1):110-20. Epub 2007/09/18.

Fantoni A, Bill RM, Gustafsson L, Hedfalk K. Improved yields of full-length functional human FGF1 can be achieved using the methylotrophic yeast Pichia pastoris. Protein expression and purification. 2007;52(1):31-9. Epub 2006/12/01.

Tornroth-Horsefield S, Wang Y, Hedfalk K, Johanson U, Karlsson M, Tajkhorshid E, et al. Structural mechanism of plant aquaporin gating. Nature. 2006;439(7077):688-94. Epub 2005/12/13.