Freeze-pressing with the X-press is an excellent method to disintegrate and release of components from organisms with a rigid cell wall, such as bacteria and plants however it is also suitable for extracting heat-labile substances from organisms without a rigid cell wall, such as animal tissue.
The following material has been successfully disrupted using the X-press technique
P=paste S=suspension T=tissue
| Animal Tissues | No.of pressings | % of disruption | State of material | |
| Human | Myeloma | 1 | 90 | T |
| Prostate carcinoma | 1 | 90 | T | |
| Liver | 1 | 90 | T | |
| Rat | Liver | 1 | 90 | T |
| Heart | 1 | 90 | T | |
| Stomach | 1 | 90 | T | |
| Intestine | 1 | 90 | T | |
| Brain | 1 | 90 | T | |
| Skin | 5 | 90 | S | |
| Muscle | 5 | 95 | T | |
| Guinea Pig | Skin | 5 | 75 | T |
| Chicken | Muscle | 5 | 75 | T |
| Bone | 4 | 60 | T | |
| Ox | Cornea | 4 | 95 | T |
| Sclerotic | 5 | 85 | S | |
| Spermatozoa | 5 | 95 | S | |
| Water snail | Foot | 3 | 95 | T |
| Torpedo | Electric organ | 5 | 85 | T |
| Protozoa | Astasia longa | 3 | 100 | S |
| Crithidia encapelti | 3 | 100 | P | |
| Prototheca zopfil | 4 | 99 | S | |
| Yeasts | ||||
| Lipomyces sp | 7 | 90 | S | |
| Candida sp | 5 | 85 | S | |
| Saccharomyces pombe | 5 | 90 | S | |
| Saccharomyces cerevisiae | 3 | 90 | P.S | |
| Botanical material | ||||
| Ragweed pollen | 2 | 95 | S | |
| Foxtail pollen | 4 | 65 | P | |
| Chlorella sp | 3 | 90 | S | |
| Lamminaria sp | 5 | 65 | S | |
| Cellulose fibre | 7 | 70 | S | |
| Phaseolus auzeus (Mung bean) | 2 | 100 | T | |
| Potato | 2 | 90 | T | |
| Fungal material | ||||
| Penicillium sp | 4 | 95 | S | |
| Aspergillus niger | 3 | 95 | S | |
| Aspergillus oryzae | 3 | 95 | S | |
| Bacteria | ||||
| Brucella sp | 5 | 80 | S | |
| Bacillus anthracis | 9 | 75 | S | |
| Bacillus megaterium | 3 | 90 | S | |
| Lactobacillus bulgaricus | 3 | 90 | P.S | |
| Clostridium chauvool | 4 | 90 | S | |
| Clostridium welchii | 3 | 90 | S | |
| Clostridium butyricum | 3 | 95 | S | |
| Clostridium perfringens | 5 | 90 | S | |
| Escherichia coli | 3 | 95 | P.S | |
| Azotobacter vinelandii | 3 | 95 | S | |
| Bordetella pertussis | 3 | 99 | P | |
| Diplococcus pneumoniae | 2 | 99 | P | |
| Leuconostoc mesenteroides | 5 | 90 | S | |
| Mycobacterium phlei | 5 | 75 | S | |
| Nocardia sp | 4 | 90 | S | |
| Proteus mirabilis | 3 | 90 | P | |
| Rhodospirillum rubum | 3 | 99 | S | |
| Salmonella typhimurium | 3 | 99 | P | |
| Staphylococcus albus | 2 | 70 | P | |
| Staphylococcus aureus | 3 | 75 | S | |
| Streptococcus pyogenes | 3 | 75 | P | |
| Streptococcus faecalis | 5 | 99 | S | |
| Cryptococcus terricolus | 5 | 99 | S |